LDN-27219 drug mechanism of action Things To Know Before You Buy
Just one particularly attention-grabbing compound is LDN-27219. Though most tTG inhibitors are designed to bind towards the protein crosslinking active internet site, LDN-27219 rather binds to your nucleotide binding pocket of the enzyme whilst it truly is in its closed-point out conformation, and stabilizes that conformation to prevent crosslinkin